Predicting ventilator-induced lung injury using a lung injury cost function
نویسندگان
چکیده
منابع مشابه
Predicting ventilator-induced lung injury using a lung injury cost function.
Managing patients with acute respiratory distress syndrome (ARDS) requires mechanical ventilation that balances the competing goals of sustaining life while avoiding ventilator-induced lung injury (VILI). In particular, it is reasonable to suppose that for any given ARDS patient, there must exist an optimum pair of values for tidal volume (VT) and positive end-expiratory pressure (PEEP) that to...
متن کاملVentilator-induced lung injury.
From the Keenan Research Center, Li Ka Shing Knowledge Institute, St. Michael’s Hospital, and the Department of Medicine and Interdepartmental Division of Critical Care Medicine, University of Toronto — both in Toronto (A.S.S.); and Dipartimento di Anestesia e Medicina degli Stati Critici, Ospedale S. Giovanni Battista Molinette, Università di Torino, Turin, Italy (V.M.R.). Address reprint requ...
متن کاملVentilator-induced lung injury.
Severe physical-trauma can lead to the development of acute respiratory distress syndrome (ARDS). Currently, the only known treatment for ARDS is mechanical ventilation. However, if mechanical ventilation is applied inappropriately further injury and malfunction of the lungs may occur, and thus, causing a ventilator induced lung injury (VILI). VILI has several manifestations including volutraum...
متن کاملVentilator-induced lung injury.
The clinical relevance of experimental ventilator-induced lung injury has recently received a resounding illustration by the Acute Respiratory Distress Syndrome Network trial that showed a 22% reduction of mortality in patients with acute respiratory disease syndrome when lung mechanical stress was lessened by tidal volume reduction during mechanical ventilation. This clinical confirmation of t...
متن کاملMechanisms of ventilator-induced lung injury.
OBJECTIVES To describe the physiologic mechanisms of ventilator-induced lung injury and to define the major ventilator and host-dependent risk factors that contribute to such injury. DATA SOURCE Basic science and clinical studies related to ventilator-induced barotrauma and lung pathophysiology. STUDY SELECTION Emphasis on controlled, experimental studies and clinical studies related to spe...
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ژورنال
عنوان ژورنال: Journal of Applied Physiology
سال: 2016
ISSN: 8750-7587,1522-1601
DOI: 10.1152/japplphysiol.00096.2016